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Eosinophilic fasciitis is rare enough that most clinicians see one case in a career. The fascia beneath the skin becomes inflamed and then thickens, the limbs stiffen, the skin takes on a puckered texture, and if it is not treated early those changes can become permanent. Glucocorticoids are the accepted first treatment. Whether to add a second immunosuppressant from the start, rather than waiting to see who relapses, is unsettled and probably always will be: the disease is far too rare to randomise, so there will never be a trial to settle it. What exists instead is cohorts, registries and case series, each reporting different things at different times, and nobody has read them as one body of evidence. This project does that and sets out what can honestly be said about the choice, including the harm of a year of steroids, which is the reason the question exists at all. The reading starts from a list already built.
Read up on eosinophilic fasciitis and how it is treated. Take one section, read the papers gathered for it, build the table that goes with it, and write that section of the review.
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